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何孟儒 博士
研究助技師
中央研究院生物化學研究所 402室
臺北市南港區115研究院路二段128號
TEL: +886-2-02-27855696 ext. 4023
FAX: +886-2-02-27889759
mho1@gate.sinica.edu.tw

維護本所生物物理公用儀器室(BIL)各項設施並提供使用者相關儀器的操作課程及技術支援。

量測生物分子間結合力與動力結合速率以及利用熱動力學方式研究交互作用力。

應用生物物理學技術探討蛋白質折疊、穩定性、構型、聚集與聚合等特性。

2003,09 - 2008,07 博士, 生物資訊與結構生物學研究所, 國立清華大學

2016,02 - present 研究助技師, 中央研究院生物化學研究所
2012,12 - 2016,02 生物物理公用儀器室經理, 中央研究院生物化學研究所
2011,10 - 2012,11 博士後研究員, 美國德州大學達拉斯西南醫學中心
2008,08 - 2011,09 博士後研究員, 中央研究院生物醫學研究所

    論文列表
A Multivalent Marine Lectin from Crenomytilus grayanus Possesses Anti-cancer Activity through Recognizing Globotriose Gb3.
Liao JH, Chien CT, Wu HY, Huang KF, Wang I, Ho MR, Tu IF, Lee IM, Li W, Shih YL, Wu CY, Lukyanov PA, Hsu ST, Wu SH Journal of the American Chemical Society (2016)
Structural Basis for the Magnesium-Dependent Activation and Hexamerization of the Lon AAA+ Protease.
Su SC, Lin CC, Tai HC, Chang MY, Ho MR, Babu CS, Liao JH, Wu SH, Chang YC, Lim C, Chang CI Structure (2016)
Uncovering the Mechanism of Forkhead-Associated Domain-Mediated TIFA Oligomerization That Plays a Central Role in Immune Responses.
Weng JH, Hsieh YC, Huang CC, Wei TY, Lim LH, Chen YH, Ho MR, Wang I, Huang KF, Chen CJ, Tsai MD Biochemistry (2015)
Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.
Chen KE, Li MY, Chou CC, Ho MR, Chen GC, Meng TC, Wang AH Structure (2015)
Structure of yeast Ape1 and its role in autophagic vesicle formation.
Su MY, Peng WH, Ho MR, Su SC, Chang YC, Chen GC, Chang CI Autophagy (2015)
Solution structure and tandem DNA recognition of the C-terminal effector domain of PmrA from Klebsiella pneumoniae.
Lou YC, Wang I, Rajasekaran M, Kao YF, Ho MR, Hsu ST, Chou SH, Wu SH, Chen C Nucleic acids research (2014)
Reciprocal allosteric regulation of p38gamma and PTPN3 involves a PDZ domain-modulated complex formation.
Chen KE, Lin SY, Wu MJ, Ho MR, Santhanam A, Chou CC, Meng TC, Wang AH Science signaling (2014)
Crystal structure of vaccinia viral A27 protein reveals a novel structure critical for its function and complex formation with A26 protein.
Chang TH, Chang SJ, Hsieh FL, Ko TP, Lin CT, Ho MR, Wang I, Hsu ST, Guo RT, Chang W, Wang AH PLoS pathogens (2013)
Human RegIV protein adopts a typical C-type lectin fold but binds mannan with two calcium-independent sites.
Ho MR, Lou YC, Wei SY, Luo SC, Lin WC, Lyu PC, Chen C Journal of molecular biology (2010)
Human pancreatitis-associated protein forms fibrillar aggregates with a native-like conformation.
Ho MR, Lou YC, Lin WC, Lyu PC, Huang WN, Chen C The Journal of biological chemistry (2006)

Updated 2013.09.12

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