Ming-Daw Tsai's Website

The main research program of Tsai lab focuses on proteins involved in cell cycle progression that are closely related with cancer and virus infection. Our structure and function studies on INK, CDK4, and Chk2 proteins shed great light on the mechanisms underlying some cancer diseases, while our enzymological characterizations of human and viral polymerases empower us to further understand the DNA damage response and repair at DNA level. In addition, we investigate the signaling pathways involving protein-phosphoprotein interactions mediated by the FHA domain, in both human (e.g. Ki67) and yeast (e.g. Rad53 and Dun1). Another project focuses on the mechanism and biological function of histone demethylases, including yeast Rph1 and human RBP2.

- 1978	Ph.D, Biochemistry & Medicinal Chemistry, Purdue University
- 1972	B.S., Chemistry, National Taiwan University, Taipei

2008,08 - 2014,08	Director, Institute of Biological Chemistry, Academia Sinica
2006,10 - 2008,08	Acting Director, Institute of Biological Chemistry, Academia Sinica
2005 -	Director, Division of Functional Genomics, Genomics Research Center
2003 -	Director, National Research Program for Genomic Medicine Core Facility Office
1995 - 2003	Director, Chemistry/Biology Interface Training Program, OSU
1993 - 2007	Director, Office of Research Campus Chemical Instrument Center, The Ohio State University
1992 - 1992	Elected Fellow, American Association for the Advancement of Science (AAAS)
1992 - 1992	Distinguished Scholar Award, Ohio State University
1985 - 1990	Camille and Henry Dreyfus Teacher-Scholar
1985 - 1985	Faculty Research Award, Ohio State Chapter of Sigma Xi
1983 - 1985	Alfred P. Sloan Fellow
1981 -	Kimberly Professor of Chemistry and Professor of Biochemistry, The Ohio State University (starting as Assistant Professor)