::::中研院生化所 ::::

我們的研究工作主要集中於兩個領域：醣化學及醣生物學和蛋白質結構與功能之間的關係。在研究過程中，應用了有機合成的方法及一些物理化學的儀器分析，歡迎有化學背景而對生命科學有興趣者加入。

- 1987	博士, 藥學院, 美國威斯康辛州威斯康辛大學麥迪遜校區
- 1977	碩士, 生化科學研究, 臺灣大學理學院碩士
- 1975	學士, 植物系, 臺灣大學

2008,07 -	特聘研究員, 中央研究院生化研究所
2006,12 -	副所長, 中央研究院生化研究所
1998,06 - 1999,05	祕書長, 臺灣生化及分子生物學會
1997,10 - 1999,10	副所長, 中央研究院生化研究所
1994,08 - 1995,07	訪問學者, 美國加州聖地牙哥
1991,08 -	教授, 臺灣大學理學院生化科學研究所
1991,07 - 2008,07	研究員, 中央研究院生化研究所
1988,04 - 1991,06	副研究員, 中央研究院生化研究所
1979,03 - 1988,03	助理研究員, 中央研究院生化研究所
1978,02 - 1979,02	藥理研究所組長, 臺灣汎球

Ditopic Complexation of Selenite Anions or Calcium Cations by Pirenoxine: An Implication for Anti-Cataractogenesis.

Liao JH, Chen CS, Hu CC, Chen WT, Wang SP, Lin IL, Huang YH, Tsai MH, Wu TH, Huang FY, Wu SH Inorganic chemistry (2011)

Structure and immunological characterization of the capsular polysaccharide of a pyrogenic liver abscess caused by Klebsiella pneumoniae: activation of macrophages through Toll-like receptor 4.

Yang FL, Yang YL, Liao PC, Chou JC, Tsai KC, Yang AS, Sheu F, Lin TL, Hsieh PF, Wang JT, Hua KF, Wu SH Journal of biological chemistry (2011)

A novel exopolysaccharide from the biofilm of Thermus aquaticus YT-1 induces the immune response through Toll-like receptor 2.

Lin MH, Yang YL, Chen YP, Hua KF, Lu CP, Sheu F, Lin GH, Tsay SS, Liang SM, Wu SH Journal of biological chemistry (2011)

The calcium-chelating capability of tetrahydrofuranic moieties modulates the cytotoxicity of annonaceous acetogenins.

Liaw CC, Liao WY, Chen CS, Jao SC, Wu YC, Shen CN, Wu SH ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

Synthesis and biological evaluation of polyenylpyrrole derivatives as anticancer agents acting through caspases-dependent apoptosis.

Fang Z, Liao PC, Yang YL, Yang FL, Chen YL, Lam Y, Hua KF, Wu SH Journal of medicinal chemistry (2010)

iscovery of New Natural Products by Intact-cell Mass Spectrometry and LC-SPE-NMR--Malbranpyrroles, Novel Polyketides from Thermophilic Fungus Malbranchea sulfurea.

Y-L. Yang, W-Y. Liao, W-Y. Liu, C-C. Liaw, C-N. Shen, Z-Y. Huang, and S-H. Wu* CHEMISTRY-A EUROPEAN JOURNAL (2009)

Phosphoproteomics of Klebsiella pneumoniae NTUH-K2044 reveals a tight link between tyrosine phosphorylation and virulence.

Lin MH, Hsu TL, Lin SY, Pan YJ, Jan JT, Wang JT, Khoo KH, Wu SH. Mol Cell Proteomics (2009)

Thermodynamic characterization of specific interactions between the human Lon protease and G-quartet DNA.

Chen SH, Suzuki CK, Wu SH* Nucleic acids research (2008)

Cytotoxic Polyketides Containing Tetramic Acid Moieties Isolated from the Fungus Myceliophthora Thermophila: Elucidation of the Relationship between Cytotoxicity and Stereoconfiguration.

Y. L. Yang, C. P. Lu, M. Y. Chen, K. Y. Chen, Y. C. Wu and S. H. Wu* CHEMISTRY-A EUROPEAN JOURNAL (2007)

Properties of Astaxanthin/Ca(2+) Complex Formation in the Deceleration of Cis/Trans Isomerization.

C. S. Chen, S. H. Wu, Y. Y. Wu, J. M. Fang and T. H. Wu Org. Lett. (2007)