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New Research Highlight on the Lon Protease
Though geographically compact, Taiwan is a hot spring of resources. In fact, researching “extreme”... Read more
Discovery of Key Autophagy Terminator that Contributes to Cell Survival and Muscle Homeostasis
A team led by Dr. Ruey-Hwa Chen, a Distinguished Research Fellow at the Institute of ... Read more
Molecular architecture of PTPN3-p38γ complex sheds light on structure-based drug design to antagonize Ras transformation
Ras signaling cascade has long been considered as an attractive therapeutic target for ... Read more
S-Nitrosylation of Endogenous Protein Tyrosine Phosphatases in Endothelial Insulin Signaling
Ming-Fo Hsu, Kuan-Ting Pan, Fan-Yu Chang, Kay-Hooi Khoo, Henning Urlaub, Ching-Feng Cheng, Geen-Dong Chang, Fawaz G. Haj, Tzu-Ching Meng Free Radical Biology and Medicine, 99:199-213 (2016)
Regulation of oncogenic KRAS signaling via a novel KRAS-integrin-linked kinase-hnRNPA1 regulatory loop in human pancreatic cancer cells
Chu PC, Yang MC, Kulp SK, Salunke SB, Himmel LE, Fang CS, Jadhav AM, Shan YS, Lee CT, Lai MD, Shirley LA, Bekaii-Saab T, Chen CS Oncogene, 35(30):3897-3908 (2016)
Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer's disease
Chen PT, Chen ZT, Hou WC, Yu LC, Chen RP Scientific Reports, 6:29760 (2016)

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