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． 創新科技和生命科學的激盪國際學術研討會
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2009/10/21  8:20 ~ 2009/10/23  13:30, 中研院 人文社會科學館 國際會議廳 (研討會)
． The 32nd A-IMBN/AMBO International Training Course - Exploring structural biology by synchrotron protein crystallography
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2009/9/30  8:30 ~ 2009/10/7  18:00, 中研院生化所、同步輻射中心(實驗) (研討會)
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最新成果發表
[ 陳佩燁 ] - Insight into the substrate length restriction of M32 carboxypeptidases: Characterization of two distinct subfamilies
(2009) Lee MM, Isaza CE, White JD, Chen RP, Liang GF, He HT, Chan SI, Chan MK.   Proteins [Epub ahead of print] () : - ....
M32 carboxypeptidases are a distinct family of HEXXH metalloproteases whose structures exhibit a narrow substrate groove that is blocked at one end. Structural alignments with other HEXXH metalloprotease-peptide complexes suggested an orientation in which the substrate is directed towards the back of the groove...
[ 吳世雄 ] - The Observation of the C-H···Osp3 Hydrogen Bond in Trisialic Acid Lactone and Its Implications for Cooperative Lactonization.(Cover Picture )
(2009) Chien-Sheng Chen, Yi-Ping Yu, Bo-Chao Lin, Jacquelyn Gervay-Hague, Jim-Min Fang, Chao-Ping Hsu, Shih-Hsiung Wu   European Journal of Organic Chemistry (2009(20)) : 3291 - ....
The cover picture shows the simulated NMR spectroscopic structure of polysialic acid polylactone....
[ 陳佩燁 ] - Polyelectrolyte multilayer films functionalized with peptides for promoting osteoblast functions
(2009) Tsai WB, Chen RP, Wei KL, Chen YR, Liao TY, Liu HL, Lai JY.   Acta Biomater. (Epub ahead of print) () : - ....
Layer-by-layer deposition of polyelectrolyte multilayer (PEM) thin films has recently been applied to biomaterial applications...
[ 蔡明道 ] - Contribution of the Reverse Rate of the Conformational Step to Polymerase β Fidelity
(2009) Marina Bakhtina, Michelle P. Roettger, and Ming-Daw Tsai   Biochemistry (48(14)) : 3197 - 3208....
A complete understanding of the kinetic mechanism of fidelity requires comparison of correct and incorrect dNTP incorporation pathways in both the forward and reverse directions. The studies presented here focus on the dNTP-induced......
[ 王惠鈞 ] - Structure, Assembly, and Mechanism of a PLP-Dependent Dodecameric l-Aspartate β-Decarboxylase.
(2009) Hui-Ju Chen, Tzu-Ping Ko, Chia-Yin Lee, Nai-Chen Wang and Andrew H.-J. Wang   Structure (17(4)) : 517 - 529....
The type-I PLP enzyme l-aspartate beta-decarboxylase converts aspartate to alanine and CO(2)....
[ 孟子青 ] [ 陳光超 ] - The organization of F-actin via the concerted regulation of Kette by PTP61F and dAbl.
(2009) Hsueh-Yen Ku, Chia-Lun Wu, Leonard Rabinow, Guang-Chao Chen, and Tzu-Ching Meng   Mol. Cell. Biol. (27 April) : Epub - ....
We have identified Kette, a key regulator of actin polymerization, as a substrate for Drosophila protein tyrosine phosphatase PTP61F, as well as for dAbl tryosine kinase....
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