Rules are Made to be Broken: How a Viral DNA Polymerase Breaks the Golden Watson-Crick Rule

Replication of DNA occurs in all living organisms and forms the basis of biological inheritance ... Read more

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Molecular Evidence to Show How Autophagy Serves as a Protective Mechanism against Oxidative Stress

Research team led by Dr. Guang-Chao Chen used fruit fly (Drosophila) adult midgut and ... Read more

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XIAP/Caspase-7 Complex as Drug-Resistant Cancer Cell Target

Research team led by Dr. Po-Huang Liang has identified a small-molecule inhibitor I-Lys, which ... Read more

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Correlation between the Glycan Variations and Defibrinogenating Activities of Acutobin and Its Recombinant Glycoforms.

Y.M. Wang, I.H. Tsai, J. M. Chen, A.C. Cheng, K.H.Khoo PLoS One, 9(6):e100354 (2014)

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An Invertebrate Warburg Effect: A Shrimp Virus Achieves Successful Replication by Altering the Host Metabolome via the PI3K-Akt-mTOR Pathway

Mei-An Su, Yun-Tzu Huang, I-Tung Chen, Der-Yen Lee, Yun-Chieh Hsieh, Chun-Yuan Li, Tze Hann Ng, Suh-Yuen Liang, Shu-Yu Lin, Shiao-Wei Huang, Yi-An Chiang, Hon-Tsen Yu, Kay-Hooi Khoo,Geen-Dong Chang, Chu-Fang Lo, Han-Ching Wang PLoS Pathogens, 10(6):e1004196 (2014)

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Self-Assembly of MinE on the Membrane Underlies Formation of the MinE-Ring to Sustain Function of the E. coli Min System

Zheng M, Chiang YL, Lee HL, Kong LR, Hsu ST, Hwang IS, Rothfield LI, Shih YL The Journal of biological chemistry [Epub ahead of print] (2014)

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