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張子文博士, Distinguished Research Fellow,Genomics Research Center, Academia Sinica
2010/3/4  15:00 ~ 16:30, 中研院生化所103大講堂 (演講)
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最新成果發表
[ 余榮熾 ] - Phosphorylation status of transcription factor C/EBP{alpha} determines cell surface poly-LacNAc branching (I antigen) formation in erythropoiesis and granulopoiesis.
(2010) Twu YC, Hsieh CY, Lin M, Tzeng CH, Sun CF, Yu LC.   Blood [Epub ahead of print] () : - ....
The cell surface straight and branched repeats of N-acetyllactosamine (LacNAc) units, called poly-LacNAc chains, characterize the histo-blood group i and I antigens, respectively. The transition of straight to branched poly-LacNAc ......
[ 蔡明道 ] - JNK-mediated turnover and stabilization of the transcription factor p45/NF-E2 during differentiation of murine erythroleukemia cells.
(2010) Lee TL, Shyu YC, Hsu PH, Chang CW, Wen SC, Hsiao WY, Tsai MD, Shen CK.   Proc Natl Acad Sci U S A. (107(1)) : 52 - 57....
Regulation of the homeostatic concentrations of specific sets of transcription factors is essential for correct programming of cell proliferation and differentiation. We have characterized the signal ......
[ 蔡明道 ] - Unambiguous determination of isobaric histone modifications by reversed-phase retention time and high-mass accuracy.
(2010) Yang L, Tu S, Ren C, Bulloch EM, Liao CL, Tsai MD, Freitas MA.   Anal Biochem (396(1)) : 13 - 22....
Methylation and acetylation of lysines are crucial posttranslational modifications that regulate gene transcription and have been shown to be misregulated in many forms of cancers. Western blot, ......
[ 陳佩燁 ] - Induction of Amyloid Fibrils by the C-Terminal Fragments of TDP-43 in Amyotrophic Lateral Sclerosis
(2010) Chen AK, Lin RY, Hsieh EZ, Tu PH, Chen RP, Liao TY, Chen W, Wang CH, Huang JJ.   J. Am. Chem. Soc. [Epub ahead of print] () : - ....
TAR DNA-binding protein 43 (TDP-43) has been identified as the major ubiquitinated aggregates in the inclusion bodies in the patients of amyotrophic lateral sclerosis (ALS) since 2006 and become a crucial culprit for ALS and related motor ......
[ 史有伶 ] - Direct MinE-membrane interaction contributes to the proper localization of MinDE in E. coli (Recommended by Faculty of 1000 Biology)
(2010) Hsieh CW, Lai HM, Lin CC, Lin TY, Hsieh TS, Shih YL   Molecular Microbiology (75(2)) : 499 - 512....
Dynamic oscillation of the Min system in Escherichia coli determines the placement of the division plane at the midcell. In addition to stimulating MinD ATPase activity, we report here that MinE can directly interact with the membrane and this interaction contributes to the proper ......
[ 孟子青 ] - The enhancement of insulin responsiveness by nitric oxide-mediated inactivation of protein tyrosine phosphatases
(2010) Ming-Fo Hsu and Tzu-Ching Meng*    J. Biol. Chem. [Epub ahead of print] () : - ....
Nitric oxide (NO) synthesis is a prerequisite for proper insulin sensitivity in insulin targeted tissues; however, the molecular basis for this process remains unclear. ......
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